Acetaminophen IV (Ofirmev) Restrictions:

• Acetaminophen injection is RESERVED for those patients who are NPO or unable to tolerate medications via mouth or enteral tube or patients being treated with acetaminophen injection for patent ductus arteriosus (PDA).
• Pharmacists may verify IV acetaminophen orders that meet the intent of the P&T policy; this includes patients that are NPO except have some oral medications on their profile but are unable to take them due to N/V, mucositis, or immediately post-op.
• Pharmacists will work with providers to convert patients from IV to oral therapy once NPO status is removed or patients are tolerating oral medications and/or full feed volumes.
• Acetaminophen injection should not be included in any order sets.
• Orders have an automatic stop date of 24 hours.  Prescribers must re-enter orders if therapy is to be continued.
• Monitor the amount of acetaminophen a patient receives per day, particularly when a combination of acetaminophen containing products are prescribed.

• UpToDate
• Recent Citations via Medline (PubMed)
• FDA Daily Med Package Inserts
• FDA Approved Drug Products
• Drugs.com/Pill Identifier