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12/18/18 LW -- Cefazolin is Now Available

From: Logan Whitfield
To: Pharmacists
Sent: Tuesday, December 18, 2018 1:33:26 PM
Subject: Cefazolin is Now Available

Hello Everyone,

ANCEF (Cefazolin) is once again available. However, continued supply will remain uncertain for the coming months.  As of this morning, all pre-op/pre-procedural areas should have their Pyxis stations restocked. The following is now in effect:

  1.Patients can once again receive cefazolin as the preferred pre-op prophylaxis in those without beta –lactam allergies.
  2.For any active infections cefazolin can again be ordered for treatment.

The following changes not related to the supply of cefazolin will REMAIN in effect based on the consensus of the Medical Executive Committee and Pharmacy and Therapeutics Committee:

  3.For all clean/clean-contaminated procedures where cefazolin, clindamycin, or vancomycin are listed on current pre/post-op orders, all post-op antibiotic orders will automatically be discontinued due to no supportive literature/guidelines. Exceptions where no automatic change will be made include:
      a.Post-op orders with 'until drain removed' in neurosurgery patients
      b.For CV surgery post-op orders ≤ 48 hours
      c.Joint replacement post-op orders ≤ 24 hours
      d.Colorectal surgery post-op orders
      e.Post-op orders for Implantation of spinal cord stimulator, generator, and lead wires ≤ 24 hours
  4.The surgery department will not utilize vancomycin or cefazolin in irrigation solutions.
  5.Pre-op antibiotic orders for cefazolin, vancomycin, or clindamycin will be automatically discontinued for percutaneous procedures involving venous puncture (e.g., tunneled lines, drain placements, etc.).
  6.If intra-op wound infection or spillage of bile/bowel contents is discovered, then antibiotics need to be customized by the practitioner.

I apologize for the delay in this information. Please contact the AMT or myself with any questions you may have.

Merry Christmas,

Philip Logan Whitfield, PharmD
PGY2 Infectious Disease Pharmacy Resident






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