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2/7/24 Tenecteplase for Acute Ischemic Stroke
February 7, 2024

From: "Carolina Woloszyn" <carolina.woloszyn@hhsys.org>
To: "Pharmacists" <allpharm@hhsys.org>
Sent: Wednesday, January 31, 2024 3:21:11 PM
Subject: Tenecteplase for Acute Ischemic Stroke
Hello all,

I have attached the educational materials, including our education information, tenecteplase kit form, and the PowerPoint presentation from our huddle today.

The Go-Live for this transition is on February 1st at 7:00 AM at Huntsville Hospital Main.

During our huddle, several questions were raised, and we want to address them to ensure clarity:

Kit Locations at HH Main:
-There will be 2 tenecteplase kits in the Emergency Department, located in A and D pods pyxis.
Additionally, 2 kits will be available on the carousel in central pharmacy.

Verification Process:
-Tenecteplase will be ordered through the NEURO Tenecteplase (TNKase) STROKE ALERT Orders. The order is configured with a maximum dose of 25 mg and will round to the nearest milligram.

Reconstitution of Tenecteplase:
-While we prefer a pharmacist to be present at the bedside to reconstitute the tenecteplase, nursing staff may proceed with reconstitution if a pharmacist is unavailable.

Pharmacist Response to Stroke Alerts:
-Pharmacists do not need to respond to stroke alerts. Our neurology team will contact pharmacy if there is a potential TNKase administration.
-If available, a pharmacist may respond to assist in the reconstitution process.

Weekend Tenecteplase Orders:
-Between 7 am and 11:30, central pharmacy is to call the NICU ascom (7-4255) to inform the pharmacist that there is an order for TNKase.


If you have any further questions or concerns, please do not hesitate to reach out.

Best Regards,

Carolina Woloszyn, Pharm.D.
PGY2 Pharmacy Resident, Critical Care
Huntsville Hospital
Department of Pharmacy






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