We now stock Paxlovid 150 mg; 100 mg RENAL dose packs and plan to dispense these as early as tomorrow, 7/28. These packs come already renally dosed and do not require the pharmacist to remove tablets prior to dispensing.

As long as adequate stock of the RENAL dose pack is sustained, there will be no need for pharmacy to modify a STANDARD pack with a reduced dose and a renal dose adjustment sticker. Just like our STANDARD Paxlovid dose packs, the RENAL packs will be dispensed from Pharmacy in their original package with a copy of the Patient Fact Sheet. Attached is the newly updated Patient Fact Sheet and an infographic for staff education. 

 

Key Points:

• Paxlovid will be dispensed from Pharmacy in its original package with a copy of the required patient fact sheet.
• The Cerner label will indicate which pack to dispense and *RENAL* is included in the description of the 150 mg; 100 mg dose packs.
• Each package will contain a full 5 day course of therapy.
  • RENAL dose packs contain one 150 mg nirmaltrelvir and one 100 mg ritonavir tablets twice daily for 5 days.
  • STANDARD dose packs contain two 150 mg nirmaltrelvir and one 100 mg ritonavir tablets twice daily for 5 days.
• Paxlovid should be stored out of sight in the patient's room and should be transferred with the patient anytime they are moved to a new unit.
• For both STANDARD and RENAL dose packs, the nurse will need to scan the barcode on the package at the bedside prior to administration. 
• Patients should swallow Paxlovid tablets whole. Do not crush, break, or chew.
• Any remaining doses of Paxlovid should be sent home with the patient at discharge. 
• Patients who started Paxlovid prior to hospital admission should use their own supply of drug if it is to be continued in the hospital.