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bisoprolol-hydroCHLOROthiazide

bisoprolol-hydroCHLOROthiazide
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Ziac TABLET, ORAL 5 mg-6.25 mg; 10 mg-6.25 mg      
Display Selective beta-Adrenergic Blocking Agents, Thiazide Diuretics Class : 12160808, 243620
Medication comments:

Beta Blockers require the following prior to each administered dose:
1) Nursing staff shall obtain the patient’s pulse and record in the EMR.
2) If the pulse is less than 50, the nurse shall obtain an apical heart rate. If the apical heart rate is less than 50, the nurse shall hold the dose and notify the provider for further orders.
3) This is applicable to all routes of administration
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: hydroCHLOROthiazide (HCTZ)
Criteria 3: Potentially inappropriate medications: drugs to be used with caution in older adults. (Table 4)
Drug(s) diuretics
Rationale May exacerbate or cause SIADH or hyponatremia; monitor sodium levels closely when starting or changing dosages in older adults.
Recommendation Use with caution
 Quality of evidence: Moderate, Strength of Recommendation: Strong
Last updated: Mar. 14, 2026
  • Look-Alike/Sound-Alike hydroCHLOROthiazide confused with hydrALAZINE, hydrOXYzine, hydroxyurea, hydroxychloroquine
UpToDate Lexidrug

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