| Per policy, these drugs may be converted from IV to PO in patients who meet criteria. |
Generic
(Brand) |
Population |
IV Dose |
PO Dose |
Notes |
azithromycin
(Zithromax) |
adult |
250 mg IV q24h |
250 mg PO q24h |
Although azithromycin has low bioavailability, it is well-distributed to tissues. |
| 500 mg IV q24h |
500 mg PO q24h |
| pediatric |
5-10 mg/kg q24h |
5-10 mg/kg q24h
(max: 500 mg/day) |
ciprofloxacin
(Cipro) |
adult |
200 mg IV q12h |
250 mg PO q12h |
Avoid concurrent divalent and trivalent cation administration 2 hours before or 6 hours after. Avoid administration with tube feeds. |
| 200 mg IV q24h |
250 mg PO q24h |
| 400 mg IV q8h |
750 mg PO q12h |
| 400 mg IV q12h |
500 mg PO q12h |
| 400 mg IV q24h |
500 mg PO q24h |
| pediatric |
10-15 mg/kg q8-12h
(max: 400 mg/dose or
40 mg/kg/day) |
10-15 mg/kg q8-12h
(max: 750 mg/dose or
40 mg/kg/day) |
clindamycin
(Cleocin) |
adult |
600 mg IV q8h |
300 mg PO q6h OR
450 mg PO q8h |
|
| 900 mg IV q8h |
450 mg PO q8h |
| pediatric |
10 mg/kg q6-8h
(max: 1800 mg/day) |
10-13.5 mg/kg q8h
(max: 2700 mg/day) |
doxycycline
(Vibramycin) |
adult |
100 mg IV q12h |
100 mg PO q12h |
Avoid concurrent divalent and trivalent cation administration 1 hours before or 4 hours after. Avoid administration with tube feeds. |
| pediatric |
2.2 mg/kg q12h
(max: 100 mg/dose) |
2.2 mg/kg q12h
(max: 100 mg/dose) |
famotidine
(Pepcid) |
may convert from IV to PO on a mg-to-mg basis. |
fluconazole
(Diflucan) |
adult |
100 mg IV q24h |
100 mg PO q24h |
|
| 200 mg IV q24h |
200 mg PO q24h |
| 400 mg IV q24h |
400 mg PO q24h |
| pediatric |
3-12 mg/kg q24h
(max: 800 mg/dose) |
3-12 mg/kg q24h
(max: 800 mg/dose) |
| folic acid |
IV (dose equivalent) |
folic acid PO (dose equivalent) |
levoFLOXacin
(Levaquin) |
adult |
500 mg IV q24h |
500 mg PO q24h |
Avoid concurrent divalent and trivalent cation administration 2 hours before or 6 hours after. Avoid administration with tube feeds. |
| 750 mg IV q24h |
750 mg PO q24h |
| pediatric |
<5 y/o: 10 mg/kg q12h,
≥5 y/o: 10 mg/kg q24h
(max: 750 mg/day) |
<5 y/o: 10 mg/kg q12h,
≥5 y/o: 10 mg/kg q24h
(max: 750 mg/day) |
levothyroxine
(Synthroid) |
may convert from IV to PO at twice the IV dose. |
linezolid
(Zyvox) |
adult |
600 mg IV q12h |
600 mg PO q12h |
|
| pediatric |
<12 y/o: 10 mg/kg q8h,
≥12 y/o: 10 mg/kg q12h
(max: 600 mg/dose) |
<12 y/o: 10 mg/kg q8h,
≥12 y/o: 10 mg/kg q12h
(max: 600 mg/dose) |
metroNIDAZOLE
(Flagyl) |
adult |
500 mg IV q8h |
500 mg PO q8h |
|
| pediatric |
10 mg/kg q6-8h
(max: 500 mg/dose or
40 mg/kg/day) OR
30 mg/kg q24h
(max: 1.5g/dose) |
10 mg/kg q6-8h
(max: 500 mg/dose or
50 mg/kg/day) |
pantoprazole
(Protonix) |
may convert from IV to PO on a mg-to-mg basis. |
| Rally Pack (MVI 10 mL, thiamine 100 mg, NS 0.9% 1000 mL) IV daily |
Multivitamin PO daily + thiamine 100 mg PO daily |
| thiamine |
IV (dose equivalent) |
thiamine PO (dose equivalent) |
voriconazole
(Vfend) |
weight based dosing
(3-4 mg/kg q12h) |
200 mg PO q12h |
| fixed (non-weight based) dosing |
may convert from IV to PO on a mg-to-mg basis. |
| last updated: 09/25/2025 |
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