FormWeb • Do Not Crush

Henry Ford Health

Approved Hospital Formulary

FormWeb QuickStart Questions or Suggestions? Pharmacy Intranet

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Brand name products with an equivalent generic may not be available to order at Henry Ford Health. For questions, contact inpatient pharmacy.

Henry Ford Health

Approved Hospital Formulary

FormWeb QuickStart Questions or Suggestions? Pharmacy Intranet

Do Not Crush

Please review each of these drugs carefully.

acetaminophen	Controlled-release Tablet
albuterol	Extended release Tablet
alendronate	Tablet - Note: Mucous membrane irritant
ALPRAZolam	Extended-release Tablet
amoxicillin	Extended
amoxicillin-clavulanate (Augmentin)	Extended‐release (b,h) Tablet
amphetamine-dextroamphetamine	Extended-release Capsule (a)
aspirin	Delayed‐release Tablet Enteric‐coated Tablet
aspirin-dipyridamole	Extended-release Capsule
atomoxetine	Capsule - Note: capsule contents can cause ocular irritation
benzonatate	Capsule - Note: swallow whole; local anesthesia of the oral mucosa; choking could occur
bisacodyl	Enteric‐coated (c) Tablet Capsule - Liquid filled
bosentan	Tablet - Note: women who are, or may become, pregnant, should not handle crushed or broken tablets
brompheniramine-phenylephrine	Extended‐release (b) Capsule
budesonide	Extended‐release Capsule Enteric‐coated (a) Capsule Tablet - Note: coating on tablet is designed to break down at pH of 7.0 or above
buPROPion	Extended-release Tablet Slow‐release Tablet
carBAMazepine	Extended‐release (a) Capsule Extended‐release (b) Tablet
carbidopa-levodopa	Extended‐release (h) Tablet
carvedilol	Extended‐release (a) Capsule - Note: may add contents of capsule to chilled, not warm, applesauce and consume immediately
cefuroxime	Tablet - Note: Taste (b)
charcoal	Enteric‐coated Tablet
cinacalcet	Tablet - Note: tablets are not scored and cutting may cause variable dosage accuracy
ciprofloxacin	Extended‐release (b) Tablet Extended‐release Tablet
clarithromycin	Extended‐release Tablet
cloNIDine	Extended‐release Tablet
cyclobenzaprine	Extended-release Capsule
cyclophosphamide	Tablet - Note: drug may be crushed but company recommends using injection
dabigatran	Capsule - Note: bioavailability increases by 75% when the pellets are taken without the capsule shell
desvenlafaxine	Extended‐release Tablet
dexmethylphenidate	Extended‐release (a) Capsule
dextromethorphan-guaifenesin	Extended-release (h) Tablet Extended‐release Tablet Slow‐release Tablet
dilTIAZem	Tablet - Note: although not in the PI, the drug has a coating that is intended to release the drug over approximately 3 hours Extended‐release (a) Capsule Extended‐release Tablet
disopyramide	Extended‐release Capsule Note: within a special capsule
divalproex sodium	Slow‐release (b) Capsule - Note: mucous membrane irritant Delayed‐release Tablet Extended‐release Tablet Extended‐release (a) Capsule
docusate	Capsule - Note: Taste (e)
donepezil	Tablet - Note: crushing the 23 mg tablet may significantly increase the rate of absorption; the 5 and 10 mg tablet are not affected
doxazosin	Extended‐release Tablet
doxycycline	Delayed‐release Capsule
DULoxetine	Extended‐release (a) Capsule - Note: may add contents of capsule to apple juice or applesauce but NOT chocolate
ergocalciferol	Liquid filled (d) Capsule
erythromycin	Enteric‐coated (b) Tablet Enteric‐coated Tablet Delayed‐release Tablet Enteric‐coated Pellets (a) Capsule
esomeprazole	Delayed‐release (a) Capsule
etravirine	Tablet - Note: tablet should be swallowed whole and not crushed; tablet may be dispersed in water
everolimus	Tablet - Note: crushed powder may cause dangerous effects to mucus membranes
felodipine	Extended‐release Tablet
fentaNYL	Slow-release Lozenge - Note: this lollipop delivery system requires the patient to slowly dissolve in mouth
ferrous gluconate	Enteric‐coated Tablet
ferrous sulfate	Enteric‐coated (b) Tablet Slow‐release Tablet
finasteride	Tablet - Note: women who are, or may become, pregnant, should not handle crushed or broken tablets
FLUoxetine	Enteric-Coated Tablet
gabapentin	Extended‐release Tablet
galantamine	Extended‐release Capsule
ganciclovir	Capsule - Note: Skin irritant
glipiZIDE	Extended‐release Tablet
guaiFENesin	Extended‐release (h) Tablet Slow‐release Tablet
guanFACINE	Extended‐release Tablet
HYDROmorphone	Extended‐release Tablet - Note: breaking, chewing, crushing, dissolving before swallowing or injecting could result in overdose
hydroxyurea	Capsule - Note: exposure to the powder may cause serious skin toxicities; healthcare workers should wear gloves to administer
hyoscyamine	Extended‐release (h) Tablet Extended‐release Capsule Controlled‐release Tablet
ibandronate	Tablet - Note: chewed, crushed, or sucked tablets may cause oropharyngeal irritation
ibuprofen	Tablet - Note: taste (e)
imatinib	Tablet - Note: Taste (h) may be dissolved in water or apple juice
indomethacin	Extended‐release (a,b) Capsule
isosorbide dinitrate	Sublingual form (g) Tablet
isosorbide mononitrate	Extended‐release (h) Tablet
isradipine	Extended‐release Tablet
lamoTRIgine	Extended‐release Tablet
levETIRAcetam	Extended‐release (b) Tablet
lithium	Extended‐release Tablet
lopinavir-ritonavir	Film‐coated (b) Tablet - Note: active ingredients are surrounded by a wax matrix to prevent healthcare exposure; women who are, or may become, pregnant, should not handle crushed or broken tablets
loratadine	Extended-release Tablet
loratadine-pseudoephedrine	Extended‐release (b) Tablet Extended‐release Tablet
memantine	Extended‐release (a) Capsule
mesalamine	Extended‐release (a) Capsule - Note: maintain pH at less than or equal to 6.0 Slow‐release (a) Tablet Delayed‐release Tablet
metFORMIN	Extended‐release Tablet
methylphenidate	Extended‐release Tablet Extended‐release (a) Capsule
metoprolol	Extended‐release (h) Tablet
metroNIDAZOLE	Extended‐release Tablet
minocycline	Extended‐release Tablet
morphine	Enteric‐coated (a; not pudding) Capsule Extended‐release (a) Capsule - Note: may add contents of capsule to apple juice or applesauce but NOT chocolate Extended‐release (a) Capsule - Note: do not give via N/G tube Extended‐release (b) Tablet
mycophenolate mofetil	Capsule, Tablet - Note: Teratogenic potential (i) Delayed‐release Tablet
mycophenolic acid	Delayed-Release Tablet
naproxen	Delayed‐release Tablet Enteric‐coated Tablet Extended‐release Tablet
nevirapine	Extended‐release (b) Tablet
niacin	Slow‐release (h) Capsule; Tablet
niCARdipine	Extended‐release Capsule
nicotine	Lozenge - Note: integrity compromised by chewing or crushing
NIFEdipine	Extended-release Tablet
nisoldipine	Extended‐release Tablet
nitroglycerin	Sublingual route (g) Tablet
omeprazole	Delayed-release (a) Capsule Delayed-Release Tablet
orphenadrine	Extended‐release Tablet
oxybutynin	Extended‐release Tablet
paliperidone	Extended‐release Tablet
pancrelipase	Enteric‐coated (a) Capsule Extended‐release (a) Capsule Delayed‐release (a) Capsule
pantoprazole	Slow-Release Tablet
PARoxetine	Extended‐release Tablet
posaconazole	Delayed‐release Tablet - Note: company literature not available to show implications
potassium chloride	Extended‐release (b) Tablet Extended‐release (b,h) Tablet - Note: to make a liquid, place tablet in 120 mL of water; disperse for 2 minutes; stir Extended‐release (a,b) Capsule
potassium citrate	Wax‐coated Tablet - prevents upper GI release
pramipexole	Extended‐release Tablet
predniSONE	Delayed-Release Tablet - Note: release is dependent upon intact coating
propafenone	Extended‐release Capsule
propranolol	Extended‐release Capsule
pseudoephedrine	Extended‐release (b) Tablet
pyridostigmine	Extended‐release (b) Tablet
QUEtiapine	Extended‐release Tablet
ranolazine	Slow-Release Tablet
ritonavir	Tablet - Note: crushing tablets has resulted in decreased bioavailability of drug (b)
rivaroxaban	Tablet - Note: Crushed tablet must be given within 4 hours
rOPINIRole	Extended‐release Tablet
sevelamer	Tablet - Note: tablets expand in liquid if broken or crushed (b)
sirolimus	Tablet - Note: pharmacokinetic NanoCrystal technology may be affected (b)
sulfaSALAzine	Delayed‐release Tablet
tamsulosin	Slow‐release Capsule
theophylline	Extended‐release Capsule - Note: contains beads that dissolve throughout the GI tract Extended‐release Tablet Slow‐release Tablet
tolterodine	Extended‐release Capsule
topiramate	Tablet/Capsule - Note: Taste (a)
traMADol	Extended‐release Tablet - Note: tablet disruption may cause a potentially fatal overdose of drug
traZODone	Extended‐release Tablet
valbenazine	Do Not Crush
valGANciclovir	Tablet - Note: Teratogenic and irritant potential (i,b)
valproic acid	Slow-Release Capsule
venetoclax	Film coated, Antineoplastic
venlafaxine	Extended‐release Capsule
verapamil	Extended‐release (h) Tablet Sustained‐release (a) Capsule Extended‐release (a) Capsule
zolpidem	Extended-release Tablet Sublingual form (g) Tablet

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