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Medications listed are available on OH EPIC Formulary, unless otherwise noted.
Not all formulary medications are available at each facility. Please refer to your local pharmacy for available inventory.
Search results for:

tbo-filgrastim

tbo-filgrastim
Drug Name Form Strength Infusion Center Available Restricted Non-formulary Ambulatory Available Interchange REMS
Granix SOLUTION, SUBCUTANEOUS 300 mcg/0.5 mL; 480 mcg/0.8 mL        

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CLASS
202400

Additional Information and Links

Restricted:

  • Inpatient formulary:
    • Releuko is the OH-preferred filgrastim biosimilar for all indications for adults and pediatrics EXCEPT:
      • Stem cell mobilization prior to (bone marrow) stem cell transplant
      • Colony stimulation post stem cell (bone marrow) transplantation
      • Pediatrics patients < 36 kg or requiring intravenous growth factor administration

 

If a filgrastim biosimilar/tbo-filgrastim (Granix) is ordered for one of the above exceptions, please initiate therapeutic interchange to filgrastim (Neupogen) at the same ordered dose.

 

If filgrastim (Neupogen), tbo-filgrastim (Granix), or any other filgrastim biosimilar is ordered besides filgrastim- AYOW (Releuko) for an indication not on the above list, please initiate the therapeutic interchange to filgrastim-AYOW (Releuko) at the same ordered dose.

 

  • Outpatient formulary:
    • Releuko is the OH-preferred filgrastim biosimilar. However, it is also driven by payer preference. 

 

Therapeutic Interchange:

Requested Dispensed

Exceptions

tbo-filgrastim (Granix) filgrastim-AYOW (Releuko)
  • Stem cell mobilization prior to (bone marrow) stem cell transplant
  • Colony stimulation post stem cell (bone marrow) transplantation
  • Pediatrics patients < 36 kg or requiring intravenous growth factor administration

Last updated: Dec. 9, 2024


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