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Medications listed are available on OH EPIC Formulary, unless otherwise noted.
Not all formulary medications are available at each facility. Please refer to your local pharmacy for available inventory.
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riTUXimab

riTUXimab
Drug Name Form Strength Infusion Center Available Restricted Non-formulary Ambulatory Available Interchange REMS
Riabni SOLUTION, INTRAVENOUS arrx 10 mg/mL        
Ruxience SOLUTION, INTRAVENOUS pvvr 10 mg/mL        
Truxima SOLUTION, INTRAVENOUS abbs 10 mg/mL        
Rituxan SOLUTION, INTRAVENOUS 10 mg/mL        

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CLASS
100000
High Alert Drug : Policy

Additional Information and Links

INPATIENT: restricted to the following non-oncologic indications:

  • Heart transplant desensitization
  • Antibody-medicated rejection: kidney transplant, kidney/pancreas transplant, heart transplant, and lung transplant
  • Systemic lupus erythematosus
  • System vasculitis (rheumatology only)
  • N-methyl-d-aspartate receptor (NMDA) encephalitis (neurology only)
  • Leucine-rich, glioma-inactivated protein 1 (LGI1) antibody associated encephalopathy (neurology only)
  • Neuromyelitis optica (NMO) (neurology only)
  • Idiopathic thrombocytopenic purpura (ITP) or thrombotic thrombocytopenic purpura (TTP)
    • For up to 4 doses given weekly
    • Will be stopped after platelet count reaches > 150 for three consecutive days

 

OUTPATIENT: restricted to Hematology/Oncology System Outpatient Infusion Centers, with criteria for use:

  • Restricted to FDA approved shared indications for biosimilars based on the reference agent.
  • Rituximab-pvvr (Ruxience) by Pfizer is the preferred Rituximab biosimilar for non-oncologic indications:
    • Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis)
    • Microscopic Polyangiitis (MPA)

Last updated: Apr. 30, 2024


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