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Medications listed are available on OH EPIC Formulary, unless otherwise noted.
Not all formulary medications are available at each facility. Please refer to your local pharmacy for available inventory.
Search results for:

filgrastim

filgrastim
Drug Name Form Strength Infusion Center Available Restricted Non-formulary Ambulatory Available Interchange REMS
Releuko (filgrastim-ayow) SOLUTION, INJECTABLE ayow 300 mcg; 480 mcg          
Zarxio (filgrastim-sndz) SOLUTION, INJECTABLE sndz 300 mcg; 480 mcg    
Neupogen SOLUTION, INJECTABLE 300; 480 mcg    
VIEW MORE Hematopoietic Agents
CLASS
201600
Additional Information and Links

Restricted:

  • Inpatient formulary:
    • Releuko is the OH-preferred filgrastim biosimilar for all indications for adults and pediatrics EXCEPT:
      • Stem cell mobilization prior to (bone marrow) stem cell transplant
      • Colony stimulation post stem cell (bone marrow) transplantation
      • Pediatrics patients < 36 kg or requiring intravenous growth factor administration

 

 If a filgrastim biosimilar/tbo-filgrastim (Granix) is ordered for one of the above exceptions, please initiate therapeutic interchange to filgrastim (Neupogen) at the same ordered dose.

 

If filgrastim (Neupogen), tbo-filgrastim (Granix), or any other filgrastim biosimilar is ordered besides filgrastim- AYOW (Releuko) for an indication not on the above list, please initiate the therapeutic interchange to filgrastim-AYOW (Releuko) at the same ordered dose.

 

  • Outpatient formulary:
    • Releuko is the OH-preferred filgrastim biosimilar. However, it is also driven by payer preference. 

 

Therapeutic Interchange:

Requested Dispensed

Exceptions:
filgrastim (Neupogen) filgrastim-AYOW (Releuko)
  • Stem cell mobilization prior to (bone marrow) stem cell transplant
  • Colony stimulation post stem cell (bone marrow) transplantation
  • Pediatrics patients < 36 kg or requiring intravenous growth factor administration
Last updated: Dec. 9, 2024

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