Medications listed are available on OH EPIC Formulary, unless otherwise noted. Not all formulary medications are available at each facility. Please refer to your local pharmacy for available inventory.
Indication: Prevention of recurrence of C. difficile infection (CDI) in individuals 18 years of age and older following antibiotic treatment for recurrent CDI
Service line: Gastroenterology, Infectious Diseases
Formulary location: Ambulatory
Service location: Clinic, Outpatient procedural area
Patient population: Adults
Prior authorization required: Yes
Restriction/criteria of use (all will apply unless specified):
At least 1 recurrence after a primary episode and had completed at least 1 round of standard-of-care oral antibiotic therapy OR had at least 2 episodes of severe CDI resulting in hospitalization within the last year.
Current episode of CDI must be controlled (˂ 3 unformed/loose stools/day for 2 consecutive days).
A positive stool test for C. difficile within 30 days.
Administration will occur 24–72 hours following completion of antibiotic course for CDI treatment.
OH Formulary