Medications listed are available on OH EPIC Formulary, unless otherwise noted. Not all formulary medications are available at each facility. Please refer to your local pharmacy for available inventory.
For diagnosis of treatment-resistant depression: confirmed by trial and failure of more than one moderately-dosed (i.e. half maximum dose or greater) antidepressant from at least 2 different classes for at least 8 weeks each for asingledepressive episode.
OR
For majordepressivedisorder (MDD)with acute suicidal ideationor behavior:confirmed inconjunctionwith atleastoneoral antidepressant.
Female atageofreproduction:negativepregnancytest.
Patient does not have diagnosis of psychotic disorder.
Patient does not have anyofthefollowing contraindications:
Aneurysmal vascular disease (including thoracic and abdominal aorta, intracranial and peripheral arterial vessels).
Limited trial:
Non-formulary (NF) but approved for use in Lafayette region during a 6-month validation period
Non-formulary (NF) but approved for use at NOMH for 6-month validation with same restriction/criteria of use:
esketamine (Spravato) intranasal use restricted to: