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Medications listed are available on OH EPIC Formulary, unless otherwise noted.
Not all formulary medications are available at each facility. Please refer to your local pharmacy for available inventory.
Search results for:

buprenorphine

buprenorphine
Drug Name Form Strength Infusion Center Available Restricted Non-formulary Ambulatory Available Interchange REMS
Belbuca FILM, BUCCAL 150 mcg; 450 mcg; 900 mcg          
Butrans FILM, EXTENDED RELEASE, TRANSDERMAL 5 mcg/hr        
Brixadi Weekly SOLUTION, EXTENDED RELEASE, SUBCUTANEOUS 8 mg/0.16 mL; 16 mg/0.32 mL; 24 mg/0.48 mL; 32 mg/0.64 mL;        
Brixadi Monthly SOLUTION, EXTENDED RELEASE, SUBCUTANEOUS 32 mg/0.64 mL; 96 mg/0.27 mL        
Sublocade SOLUTION, EXTENDED RELEASE, SUBCUTANEOUS 100 mg/0.5 mL        
Brixadi Monthly SOLUTION, EXTENDED RELEASE, SUBCUTANEOUS 128 mg/0.36 mL            
Sublocade SOLUTION, EXTENDED RELEASE, SUBCUTANEOUS 300 mg/1.5 mL        
Buprenex SOLUTION, INJECTABLE 0.3 mg/mL        
Buprenorphine HYDROCHLORIDE TABLET, SUBLINGUAL 2 mg; 8 mg        


Additional Information and Links

Belbuca (buprenorphine) buccal film OH Epic Formulary with restrictions:

  • Indication: microdosing strategy for opioid use disorder or opioid dependence
  • Service Line: all providers
  • Formulary Location: Inpatient
  • Service location: Inpatient
  • Patient Population: Adults
  • Prior Authorization Required: no

Brixadi (buprenorphine) extended release subcutaneous injection OH Epic Formulary with restrictions:

  • Indication: For the treatment of moderate to severe opioid use disorder in patients who have initiated treatment with a single dose of a transmucosal buprenorphine product or who are already being treated with buprenorphine.
  • Service line: All providers
  • Formulary location: Outpatient
  • Service location: Clinic
  • Patient population: Adults (age ≥ 18 years)
  • Prior authorization required: Yes
  • Restriction/criteria of use (all will apply unless specified):
    • Diagnosis of opioid dependence
    • Patient meets one of the following:
      • Patient is switching from another non-transmucosal buprenorphine-containing product (e.g., Sublocade)
      • Patient has tolerated a single 4 mg dose of transmucosal buprenorphine-containing product OR currently is being treated with a transmucosal buprenorphine-containing product
    • Medical justification supports inability to continue to use transmucosal (e.g., sublingual, buccal) formulations of buprenorphine as evidenced by one of the following:
      • Documentation of non-compliance to transmucosal formulations of buprenorphine
      • Treatment failure with transmucosal formulations of buprenorphine
      • History of diversion with buprenorphine medication-assisted treatment (MAT) products
      • Contraindication(s) or clinically significant adverse effects to the excipients of transmucosal formulations of buprenorphine
    • Healthcare settings and pharmacies that order and dispense buprenorphine (Brixadi) must be certified and comply with the buprenorphine (Brixadi) REMS requirements

Last updated: Jul. 11, 2025


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