Approved Hospital Formulary
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Approved Hospital Formulary
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prothrombin complex concentrate

prothrombin complex concentrate
Brand names: Kcentra, PCC
Form Strength
POWDER FOR INJECTION, INTRAVENOUS 500 Factor IX units/vial

VIEW MORE Hemostatics
CLASS
202816

Additional Information:

Order via ANTITHROMBOTIC REVERSAL order set (order set 1941)

Reversal Guidelines:

Reversal in adult patients on warfarin, dabigatran, rivaroxaban, or abixaban: See Reversal Guideline 900.5010

Pediatric: Reversal of warfarin: See Reversal Guideline 900.5866

Massive Transfusion Protocol, see protocol 915.6150 and Pharmacologic Adjuncts for Massive Transfusion

       5/2022: P&T Approval of fixed dosing of Kcentra for warfarin reversal for major bleeding or emergent surgery and fixed dose Kcentra for factor Xa-inhibitor reversal for major bleeding.   

Other Guidelines:

Anticoagluation Management while on ECMO, see protocol 922.5063

May have limited inventory. See Antidote Policy 916.3804

Correcting coagulopathy using ROTEM: see Trauma Guideline 901.5001

For further information, see Drug Monograph.

How to Enter and Verify Blood Factor Product Orders: See Pharmacist Tip Sheet


Last updated: May. 31, 2022







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