Approved Hospital Formulary
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Approved Hospital Formulary
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piperacillin-tazobactam

piperacillin-tazobactam
Brand names: Zosyn
Form Strength
POWDER FOR INJECTION, INTRAVENOUS 2 g-0.25 g; 3 g-0.375 g; 4 g-0.5 g; 36 g-4.5 g
SOLUTION, INTRAVENOUS 2 g-0.25 g/50 mL; 3 g-0.375 g/50 mL; 4 g-0.5 g/100 mL


Additional Information:
Drug Name Common Side Effects

piperacillin-tazobactam

  • GI: diarrhea, constipation, nausea
  • headache
  • insomnia

Piperacillin-tazobactam (Zosyn) is non-formulary and will only be allowed when inventories of cefepime are depleted during a shortage.  Orders for Zosyn will be changed per Protocol 900.6000 Patient Care Therapeutic Interchange Protocols  

For use during shortage only:

  • If extravasation occurs, please refer to Elsevier Clinical Skills: Prevention and Management of Extravasations for the Treatment and Management of Extravasations
  • Renal dose adjustment protocol: See Protocol 900.6511

Last updated: May. 16, 2023







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