Approved Hospital Formulary
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Approved Hospital Formulary
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alteplase

alteplase
Brand names: Activase, Cathflo Activase, tPA
Form Strength
POWDER FOR INJECTION, INJECTABLE 2 mg
POWDER FOR INJECTION, INTRAVENOUS 50 mg; 100 mg

VIEW MORE Thrombolytic Agents
CLASS
201220

Additional Information:

Line Care:

CathFlo  for declotting central venous catheter: See Policy 904.4009

Stroke Protocol/Guidelines - NOTE: tenecteplase is the formulary thrombolytic for treatment of ischemic stroke at Legacy, where indicated

Eligibility for IV Treatment with a Thrombolytic for Stroke: See Policy 900.5007

Nursing management of stroke in ED: See Policy 905.5002

Code Stroke for Adult Admitted Patients: See Policy 900.6522

Other Protocol/Guidelines: 

Thrombolytic therapy for massive/submassive pulmonary embolism (PE): See Policy 900.5003

Use of t-PA and Dornase alpha in pleural infections (Intrapleural administration): See Policy 900.3028

Alteplase for therapeutic indications may only be ordered via Order Set (including stroke, PE, DVT, pulmonary instillation).  See 900.3233 Medications: Orders

Reversal/Discontinuation

Neuraxial Anesthesia and Anticoagulation: see Guideline 900.5681

Reversal of tPA: See Reversal Guideline 900.5010


Last updated: Sep. 24, 2024







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