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Approved Formulary

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linezolid

linezolid

Brand names: Zyvox

Form	Strength
SOLUTION, INTRAVENOUS	2 mg/mL
TABLET, ORAL	600 mg

Display Oxazolidinones Class: 08122824

Medication comments:

Per policy, these drugs are subject to renal dosing adjustments by pharmacy.
Generic + Route (Brand) • Indications	Usual Adult Dose Comments	Renal Dosage Adjustments
linezolid IV/PO (Zyvox^©)	400-600 mg q12h	No adjustment necessary

Per policy, these drugs may be converted from IV to PO in patients who meet criteria.
Generic (Brand)	Population	IV Dose	PO Dose	Notes
linezolid (Zyvox)	adult	600 mg IV q12h	600 mg PO q12h
linezolid (Zyvox)	pediatric	<12 y/o: 10 mg/kg q8h, ≥12 y/o: 10 mg/kg q12h (max: 600 mg/dose)	<12 y/o: 10 mg/kg q8h, ≥12 y/o: 10 mg/kg q12h (max: 600 mg/dose)

Enteral Drug Administration notes.
Generic (Brand)	Comments and Considerations	Recommendations for Administration with Enteral Nutrition
linezolid (Zyvox)	Oral suspension rapidly and completely absorbed.	Change to oral suspension

Last updated: Apr. 17, 2024

Renal Adjustment Policy linezolid subject to adjustments by pharmacy.
IV to PO Conversion Policy Policy

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Memorial Hospital.
While others may view accessible pages, Iredell Memorial Hospital makes no warranty, express or implied,
as to the use of this information outside of Iredell Memorial Hospital.
The content of this policy and procedure document serves as guidance to the delivery of quality patient care.
Care providers are expected to exercise critical thinking and situational awareness skills,
and in specific situations to take such action as is necessary for the delivery of quality patient care.