Search results for:

famotidine

famotidine
Brand names: Pepcid
Form Strength
LIQUID, ORAL 40 mg/5 mL
SOLUTION, INTRAVENOUS 20 mg/2mL
TABLET, ORAL 10 mg; 20 mg
Display Histamine H2-Antagonists Class: 562812
Medication comments:

Refrigerator item (injection) 

Per policy, these drugs are subject to renal dosing adjustments by pharmacy. 
Generic + Route
(Brand)
• Indications		 Usual Adult Dose
Comments		 Renal Dosage Adjustments
famotidine IV/PO
(Pepcid©)		 40 mg q24h
or
20 mg q12h		 IV Adjustments:
CrCl > 50: 20 mg BID
CrCl < 50: 20 mg daily
PO Adjustments:
CrCl > 60: 20 mg daily or BID
CrCl 30-60: 10-20 mg daily
CrCl < 30: 10 mg daily or 20 mg QOD
Per policy, these drugs may be converted from IV to PO in patients who meet criteria.  
famotidine (Pepcid) may convert from IV to PO on a mg-to-mg basis.
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: famotidine (Pepcid)
Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3)
Drug(s) ⇆ disease or syndrome H2-receptor antagonists ⇄ Delirium
Rationale Avoid in older adults with or at high risk of delirium because of the potential of inducing or worsening delirium.
Recommendation Avoid
 Quality of evidence: Low, Strength of Recommendation: Strong
 
Criteria 5: medications that should be avoided or have their dosage reduced with varying levels of kidney function in older adults. (Table 6)
CrCl (mL/min) at which action is required <50
Rationale Mental status changes
Recommendation Reduce dose
 Quality of evidence: Moderate, Strength of Recommendation: Strong
Last updated: Sep. 19, 2025
  • Renal Adjustment Policy famotidine subject to adjustments by pharmacy.
  • IV to PO Conversion Policy Policy
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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