dexmedetomidine should generally not be interrupted during procedures unless there is a specific physician order.
Per policy, these medications require cardiac and/or special monitoring. (KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes
dexmedetomidine (Precedex) IV infusion
Y
N
N
N
N
N
N
N
Iredell Memorial Hospital ICU Adult Infusion Guidelines
The following orders are intended to provide a specific, safe, and effective means of initiating and titrating medications for critically ill patients. Physicians may modify doses and/or parameters as necessary pending patients' status.For all medications listed below, the responsible LIP is to be notified if unable to titrate or the maximum dose is reached andgoals of therapy are not met.
Drug Name
Onset
Preparation
Compatible fluids
dexmedetomidine (Precedex)
1 min
400 mcg/100 mls NS 200 mcg/50 mls NS
NS ONLY
Starting Dose for ICU Sedation
Titration Guidelines (for increasing and decreasing doses) with Maximum dose
Begin infusion at 0.2 mcg/kg/hr.
titrate by 0.1 mcg/kg/hr every 30 min to -2 RASS sedation score. Monitor for hypertension. Max dose = 1.4 mcg/kg/hr.
Drug Name
Onset
Preparation
Compatible fluids
dexmedetomidine (Precedex) ED ONLY
1 min
400 mcg/100 ml NS 200 mcg/50 ml NS
NS ONLY
Starting Dose for ICU Sedation
Titration Guidelines (for increasing and decreasing doses) with Maximum dose
Begin infusion at 0.4 mcg/kg/hr.
titrate by 0.1 mcg/kg/hr every 30 min to -2 RASS sedation score. Monitor for hypertension. Max dose = 1.4 mcg/kg/hr.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
IV infusion
ED ONLY