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Search results for:
acyclovir
acyclovir
Brand names:
Zovirax
Form
Strength
CAPSULE, ORAL
200 mg
SOLUTION, INTRAVENOUS
50 mg/mL
TABLET, ORAL
800 mg
Display
Nucleosides and Nucleotides
Class:
081832
Medication comments:
Pediatric IV prep/admin
Renal Adjust
Extravasation Tx
Enteral notes
Per policy, these drugs are subject to renal dosing adjustments by pharmacy.
Renal Dosing Program
View all
Generic + Route
(Brand)
• Indications
Usual Adult Dose
Comments
Renal Dosage Adjustments
acyclovir
IV
(
Zovirax
©
)
• Herpes Zoster
• HSV encephalitis
10 mg/kg q8h
Actual weight, use IBW for obese pts (BMI > 30)
CrCl > 50: No adjustment necessary
CrCl 25-50: 10 mg/kg q12h
CrCl 10-24.5: 10 mg/kg q24h
CrCl < 10: 5 mg/kg q24h
HD/PD: 2.5-5 mg/kg q24h
acyclovir
IV
(
Zovirax
©
)
• Herpes Simplex
5 mg/kg q8h
Actual weight, use IBW for obese pts (BMI > 30)
CrCl > 50: No adjustment necessary
CrCl 25-50: 5 mg/kg q12h
CrCl 10-24.5: 5 mg/kg q24h
CrCl < 10: 2.5 mg/kg q24h
HD/PD: 2.5-5 mg/kg q24h
acyclovir
PO
(
Zovirax
©
)
200-800 mg 5x/day
CrCl > 25: No adjustment necessary
CrCl 10-25: 200-800 mg q8h
CrCl < 10: 200 mg q12h
HD: 200 mg q12h
PD: 600-800 mg daily
Adult Extravasation Management
Policy
View all
Generic (Brand)
Vesicant / irritant
Local Care
acyclovir
(
Zovirax
)
Irritant
Enteral Drug Administration notes.
View all
Generic
(Brand)
Comments and Considerations
Recommendations for Administration with Enteral Nutrition
acyclovir
(
Zovirax
)
Commercially available suspension combined with Osmolite resulted in clogging 8 Fr, but not 20 Fr feeding tubes
Disperse tablet in 20 mL water. Do NOT administer suspension through feeding tube.
Last updated:
May. 1, 2024
Renal Adjustment Policy
acyclovir subject to adjustments by pharmacy.
UpToDate
FDA DailyMed Package Insert
MedLinePlus (Patient Information)
MSDS Online
(Brand)
• Indications
Comments
(Zovirax©)
• Herpes Zoster
• HSV encephalitis
Actual weight, use IBW for obese pts (BMI > 30)
CrCl 25-50: 10 mg/kg q12h
CrCl 10-24.5: 10 mg/kg q24h
CrCl < 10: 5 mg/kg q24h
HD/PD: 2.5-5 mg/kg q24h
(Zovirax©)
• Herpes Simplex
Actual weight, use IBW for obese pts (BMI > 30)
CrCl 25-50: 5 mg/kg q12h
CrCl 10-24.5: 5 mg/kg q24h
CrCl < 10: 2.5 mg/kg q24h
HD/PD: 2.5-5 mg/kg q24h
(Zovirax©)
CrCl 10-25: 200-800 mg q8h
CrCl < 10: 200 mg q12h
HD: 200 mg q12h
PD: 600-800 mg daily
(Brand)
(Zovirax)