FormWeb • sodium chloride IV solution (Hypertonic)

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Sodium Chloride 3%, Intravenous

sodium chloride IV solution (Hypertonic)

Restricted Medications IV infusion

Drug Name	Form	Strength	Non-Formulary	Restricted	TX Sub	Notes
Sodium Chloride 3%, Intravenous	SOLUTION, INTRAVENOUS	Sodium Chloride 3%

Display Replacement Preparations Class : 401200

High Alert Drug : Policy

Medication comments:

High Alert Drug: Hypertonic sodium chloride
• Stocked only in pharmacy. • Dosing guidelines with limit of one bag dispensed per order. • Electronic order set.

Per policy, these medications require cardiac and/or special monitoring. (KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes	CCU, OR, PACU, CCL, ED	PCU	2N (Tele)	1N (Tele), 3N (Tele)	Med/Surg (1N w/o Tele, 3N w/o Tele, 4N, 5N)	BirthPlace	SNF	ICS	OPS
sodium chloride 3% IV infusion IV Infusion Key: policy, order set	Y	Y (if asympto-matic)	Y (if asympto-matic)	Y (if asympto-matic)	Y (if asympto-matic)	Y (if asympto-matic)	N	Y (if asympto-matic)	N

How to make 3% saline using NS and concentrated NaCl:
component	volume
Normal Saline	500 ml
Sodium Chloride 23.4%	51.5 ml
total volume	551.5 ml

Adult Extravasation Management
sodium chloride > 3%

Agent type:	Non-Chemotherapeutic
Vesicant/Irritant:	Vesicant
Local Care:	Warm compress
Antidote:	Hyaluronidase (200 units/mL)
Antidote link(s):

Last updated: May. 4, 2026

UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.