CISatracurium should generally not be interrupted during procedures unless there is a specific physician order.
Refrigerator item
High Alert Drug: Neuromuscular blocking agents
• Stored in lidded or locked-lidded containers and labeled as PARALYZING AGENT in large red lettering in ICU, CCU, ED, Endo, OR, holding room, cath lab holding room. • Two RNs independently verify dosage prior to administration. • Storage bins labeled with fluorescent orange sticker as WARNING: PARALYTIC AGENT CAUSES RESPIRATORY ARREST in Pharmacy, ICU, CCU, ED, Endo, OR, holding room, cath lab holding room. • Separate locked drawer in Anesthesia cart and storage bins labeled with fluorescent orange sticker as WARNING: PARALYTIC AGENT CAUSES RESPIRATORY ARREST in Anesthesia.
Per policy, these medications require cardiac and/or special monitoring. (KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes
CISatracurium (Nimbex) IV Push, IV Infusion Key: order set, vent
Y
N
N
N
N
N
N
N
Iredell Memorial Hospital ICU Adult Infusion Guidelines
The following orders are intended to provide a specific, safe, and effective means of initiating and titrating medications for critically ill patients. Physicians may modify doses and/or parameters as necessary pending patients' status.For all medications listed below, the responsible LIP is to be notified if unable to titrate or the maximum dose is reached andgoals of therapy are not met.
Drug Name
Onset
Preparation
Compatible fluids
CISatracurium (Nimbex)
2-3 min
100 mg/250 ml
NS or D5W
Starting Dose for ICU Sedation
Titration Guidelines (for increasing and decreasing doses) with Maximum dose
For ICU paralysis: Begin infusion at 1 mcg/kg/min.
For ICU paralysis: titrate by 1mcg/kg/min every 10 min to TOF 2-3 twitches. Max = 10 mcg/kg/min. Must be on MECHANICAL VENTILATION and must be INDEPENDENTLY VERIFIED by TWO RN'S.
Last updated: Apr. 17, 2024
Look-Alike/Sound-Alike CISatracurium confused with atracurium
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• Two RNs independently verify dosage prior to administration.
• Storage bins labeled with fluorescent orange sticker as WARNING: PARALYTIC AGENT CAUSES RESPIRATORY ARREST in Pharmacy, ICU, CCU, ED, Endo, OR, holding room, cath lab holding room.
• Separate locked drawer in Anesthesia cart and storage bins labeled with fluorescent orange sticker as WARNING: PARALYTIC AGENT CAUSES RESPIRATORY ARREST in Anesthesia.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
IV Push, IV Infusion Key: order set, vent