This new preparation is a long-acting vinCRIStine preparation dosed as 2.25 mg/sq. meter intravenously over 1 hour, once weekly. It is FDA approved to treat resistant ALL. Preparation is very cumbersome, and includes mixing the drug and the liposomal component together in a temperature controlled water bath for approximately 90 minutes. The cost is nearly $12,000 for 1 weekly dose. The drug was classified as non-formulary, not stocked for inpatient and hospital outpatient use. If ever needed, advanced planning will have to take place.
This new preparation is a long-acting vinCRIStine preparation dosed as 2.25 mg/sq. meter intravenously over 1 hour, once weekly. It is FDA approved to treat resistant ALL. Preparation is very cumbersome, and includes mixing the drug and the liposomal component together in a temperature controlled water bath for approximately 90 minutes. The cost is nearly $12,000 for 1 weekly dose. The drug was classified as non-formulary, not stocked for inpatient and hospital outpatient use. If ever needed, advanced planning will have to take place.
Reviewed: January 28, 2014