Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
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macitentan-tadalafil

macitentan-tadalafil
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Opsynvi TABLET, ORAL 10 mg-20 mg | 10 mg-40 mg    
Comments:

Non-Formulary; interchange to individual components

 

ORDERED FORMULATION THERAPEUTIC INTERCHANGE
macitentan-tadalafil (Opsynvi)                        
  • 10 mg-20 mg tablet                                                 
  • 10 mg-40 mg tablet                                       
 macitentan (Opsumit) AND tadalafil (Adcirca)
  • ONE 10 mg macitentan tablet PLUS ONE 20 mg tadalafil tablet
  • ONE 10 mg macitentan tablet PLUS TWO 20 mg tadalafil tablets 
Last updated: Oct. 17, 2025
Rhazdrugs macitentan-tadalafil






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