Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
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dextromethorphan-Bupropion ER

dextromethorphan-Bupropion ER
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Auvelity TABLET, EXTENDED RELEASE, ORAL 45 mg/105 mg    
Comments:

Auvelity should be automatically interchanged to the individual components. Inpatients may use home supply, especially in cases when liquid dextromethorphan is not feasible or desired.

 

Plain dextromethorphan products (Delsym) or dextromethorphan-guafenesin (Robitussin DM) may be used for the interchange based on available stock.

ORDERED FORMULATION

THERAPEUTIC INTERCHANGE

Dextromethorphan/Bupropion ER

  • Dextromethorphan 45 mg/ bupropion 105 mg ER (Auvelity) once daily or BID

Dextromethorphan PLUS Bupropion ER

  • Dextromethorphan 45 mg (given as Robitussin DM Cough; guaifenesin-dextromethorphan 100-10 mg/5mL) 22.5 mL once daily or BID                                                                    PLUS                                                     
  • Bupropion 100 mg/12 hr ER tablet once daily or BID

 

Reviewed: April 2023 (Auvelity)

Last updated: Apr. 30, 2025






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