Oseltamivir
Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information. CrCl calculation policy available here.
Drug
Usual Dose
CrCl (mL/min)
Renal Dose Adjustment
Oseltamivir (PO)
Influenza prophylaxis
75 mg q24h
31-60
11-30
<11
HD
30 mg q24h
30 mg q48h
30 mg x1
30 mg x1, then 30 mg after alternate HD sessions
Influenza treatment
75 mg q12h
30 mg q12h
30 mg x1, then 30 mg after each HD session
Automatic Stop: 5 day stop date for oseltamivir orders.
Reviewed: 28 Feb 2017 (Renal adjustments)
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Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information. CrCl calculation policy available here.
Drug
Usual Dose
CrCl (mL/min)
Renal Dose Adjustment
Oseltamivir (PO)
Influenza prophylaxis
75 mg q24h
31-60
11-30
<11
HD
30 mg q24h
30 mg q48h
30 mg x1
30 mg x1, then 30 mg after alternate HD sessions
Influenza treatment
75 mg q12h
31-60
11-30
<11
HD
30 mg q12h
30 mg q24h
30 mg q48h
30 mg x1, then 30 mg after each HD session
Automatic Stop: 5 day stop date for oseltamivir orders.
Reviewed: 28 Feb 2017 (Renal adjustments)