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Kcentra

prothrombin complex
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Kcentra POWDER FOR INJECTION, INTRAVENOUS      
Comments:

Kcentra is the PREFERRED prothrombin complex concentrate (PCC) product for emergent reversal of oral anticoagulants AND life-threatening bleeding unresponsive to alternative therapy. See prescriber restrictions below.

Interchange orders from FEIBA to Kcentra unless contraindicated.

 

Emergent Reversal of Oral Anticoagulants

Kcentra Order Verification Guide (HH Main)

Kcentra Order Verification Guide - Madison (After Hours)

 

Approved Kcentra prescribers:

cardiologists, cardiovasular surgeons, emergency department physicians, hematologists, medical intensivists, neurologists, neurosurgeons, vascular surgeons, and trauma surgeons.

 

Reviewed: August 27, 2013

Updated: 28 March 2017, 25 April 2017, 28 Aug 2018, November 2025

 

 

Kcentra Formulary Update 2025.pdf

Last updated: Jan. 28, 2026






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