Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
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Cefotaxime

cefotaxime
  • Restricted Claforan --> Restricted to NO SUB orders.
  • Restricted Claforan --> DO NOT convert Claforan to Rocephin in PEDS (≤ 12 years old).
  • Restricted Claforan --> DO NOT interchange Claforan in cases of pre-op surgery doses or in 'taxmet' regimens.
  • Therapeutic Interchange Cephalosporin (Third Generation Injectable) Formulary
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Claforan POWDER FOR INJECTION, INJECTABLE 1 g, 2 g    


Comments:

 

ORDERED FORMULATION

THERAPEUTIC INTERCHANGE

NOTES

cefotaxime (Claforan)

  • 1 g q 12 hr (2 g/d)
  • 1 g q 8 hr (3 g/d)
  • 1 g q 6 hr (4 g/d)
  • 1 g q 4 hr (6 g/d)
  • 2 g q 12 hr (4 g/d)
  • 2 g q 8 hr (6 g/d)
  • 2 g q 6 hr (8 g/d)
  • 2 g q 4 hr (12 g/d)

cefTRIAXone (Rocephin)

  • 1 g q 24 hr (1 g/d)
  • 1 g q 24 hr (1 g/d)
  • 1.5 g q 24 hr (1.5 g/d)
  • 1 g q 12 hr (2 g/d)
  • 1.5 g q 24 hr (1.5 g/d)
  • 2 g q 24 hr (2 g/d)
  • 2.5 g q 24 hr (2.5 g/d)
  • 2 g q 12 hr (4 g/d)

 

  • Do not interchange cefTRIAXone for cefotaxime in cases of pre-op surgery doses or in “taxmet” regimens;
  • Do not convert Claforan to Rocephin in peds (≤ 12 y/o)

Standard Pediatric/Neonatal concentrations for syringes


Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information.  CrCl calculation policy available here.

 


Last updated: Jul. 16, 2024







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