2 g q6-8h (use q6h for CNS and febrile neutropenia)
10-29
<10/HD
CRRT
1 g q 6-8h
1 g IV q 12h, after HD
2g x1 then 2 g q12h or 1 g q8h
CAYSTON -- Patient must have own Altera Inhaler to use with drug. Currently drug is only shipped directly to patient or MD, hospital cannot order. Non-formlary, not stocked.
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Automatic renal adjustment per guidelines.
Drug
Usual Dose
CrCl (mL/min)
Dose Adjustment
Aztreonam
Mild Infections (UTI)
1 g IV q 8h
10-29
<10/HD
CRRT
1 g IV q 12h
1 g IV q 24h, after HD
2g x1 then 1 g q8-12h
Moderate to Severe Infections (CNS,
IAI, PNA)
2 g q6-8h (use q6h for CNS and febrile
neutropenia)
10-29
<10/HD
CRRT
1 g q 6-8h
1 g IV q 12h, after HD
2g x1 then 2 g q12h or 1 g q8h
CAYSTON -- Patient must have own Altera Inhaler to use with drug. Currently drug is only shipped directly to patient or MD, hospital cannot order. Non-formlary, not stocked.
Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information. CrCl calculation policy available here.
Updated: 28 Feb 2017 (Renal Adjustments)