Approved Hospital Formulary
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Medications not yet evaluated by P&T are considered NON-FORMULARY. Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step!
Please be sure to document all clinical activities daily.
Please be sure to document all clinical activities daily.
Approved Hospital Formulary
Search results for:
4-Factor PCC, 4 Factor PCC
prothrombin complex
- Restricted Miscellaneous Programs
Last updated: Jan. 28, 2026
- Black Box Warning: Arterial and venous thromboembolic complications
Kcentra is the PREFERRED prothrombin complex concentrate (PCC) product for emergent reversal of oral anticoagulants AND life-threatening bleeding unresponsive to alternative therapy. See prescriber restrictions below.
Interchange orders from FEIBA to Kcentra unless contraindicated.
Emergent Reversal of Oral Anticoagulants
Kcentra Order Verification Guide (HH Main)
Kcentra Order Verification Guide - Madison (After Hours)
Approved Kcentra prescribers:
cardiologists, cardiovasular surgeons, emergency department physicians, hematologists, medical intensivists, neurologists, neurosurgeons, vascular surgeons, and trauma surgeons.
Reviewed: August 27, 2013
Updated: 28 March 2017, 25 April 2017, 28 Aug 2018, November 2025
Kcentra Formulary Update 2025.pdf