Approved Hospital Formulary
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Brand name products with an equivalent generic may not be available to order at Henry Ford Health. For questions, contact inpatient pharmacy.
Approved Hospital Formulary
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tenecteplase

tenecteplase
Drug Name Form Strength Clinic Use Only Inpatient Restrictions Outpatient Restrictions Non-Formulary
TNKase POWDER FOR INJECTION, INJECTABLE 50 mg        

High Alert Drug : Policy

Dosing information for treatment of STEMI

Tenectaplase
Patient Actual Body Weight (kg) TNKase  (mg) Volume to be administered (mL)
< 60 30 6
≥ 60 to < 70 35 7
≥ 70 to < 80 40 8
≥ 80 to < 90 45 9
≥ 90 50 10

Administration

  • Dilute tenecteplase powder with 10 mL of Sterile Water for Injection provided in the kit. Swirl vial gently until dissolved. DO NOT SHAKE. 
  • Withdraw prescribed dose and administer as IV push over 5 seconds via dedicated line.
  • Precipitation may occur in IV line containing dextrose. Flush line with NaCl 0.9% prior to and after administration

Last updated: Apr. 1, 2020


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