Approved Formulary
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Approved Formulary
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nirsevimab (cvx 306)

nirsevimab (cvx 306)
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-formulary Interchange
Beyfortus INJECTION 50 mg; 100 mg      

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CLASS
m00254

Comments:

Nirsevimab is a RESTRICTED formulary item.  A one time discharge dose may be given within 72 hours of discharge to patients who meet the below criteria from October to February.

Dr. Brett Turner (pulmonologist) or his designee must approve all doses given.  No other uses of Palivizumab are allowed at Children's of Alabama.

Patients who meet the below criteria are eligible to receive Palivizumab:

Gestational Age

 

Current Age

 

Additional Criteria

 

Less than 29 weeks

 

Less than 12 months

 

 

 

Less than 32 weeks

 

Less than 12 months

 

Chronic Lung disease of prematurity*

 

Less than 32 weeks

 

Less than 24 months

 

Chronic Lung Disease of Prematurity* AND required medical support** during the 6 month period before the start of the second RSV season

 

Any gestational age AND

 

Less than 12 months

 

Hemodynamically significant Congenital Heart Disease***

 

Any gestational age AND

 

Less than 12 months

 

Neuromuscular or congenital anomaly that impairs clearance of secretions

 

Any gestational age AND

 

Less than 24 months

 

Profoundly immunocompromised****

 

*Chronic Lung Disease of prematurity: Gestational age <32 weeks, 0 days and a requirement for >21% oxygen for at least the first 28 days after birth

**Medical support: chronic corticosteroid therapy, diuretic therapy, bronchodilator therapy or supplemental oxygen

***Hemodynamically significant Congenital Heart Disease: acyanotic heart disease patients who are receiving medication to control congestive heart failure and will require cardiac surgical procedures and infants with moderate to severe pulmonary hypertension. NOTE: patients should not receive palivizumab while on cardiac bypass or extracorporeal membrane oxygenation. A dose should be considered after cardiac bypass, at the conclusion of extracorporal membrane oxygenation, or after cardiac transplantation.

****Profoundly immunocompromised: children who undergo solid organ or hematopoietic stem cell transplantation, are receiving chemotherapy, or are immunocompromised because of other conditions

 


Last updated: Nov. 29, 2023


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