Approved Formulary
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Approved Formulary
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meropenem

meropenem
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-formulary Interchange
Merrem POWDER FOR INJECTION 500 mg and 1 g vials      


Comments:

Meropenem is a RESTRICTED formulary medication.  Use is restricted to patients who meet one of the approved indications.

*ALL use requires ID consult PRIOR to use even for "approved" indications*.

COA approved indications:

Culture/Sensitivity documenting ESBL infections

H/O or current infection with organism that is confirmed resistant to at a minimum cefepime and/or zosyn

Gram negative infection involving the CNS (Pseudomonas, Enterobacter, Klebsiella)

Febrile neutropenic patient meeting the following criteria: Fever > 72 hours + hemodynamic instability and/or resp distress despite adequate GNR coverage requiring transfer to higher level of care AND abdominal symptoms with an allergy/intolerance to Zosyn

Sepsis with no source meeting the following criteria: H/O ESBL OR abdominal sepsis with prolonged exposure to cefepime or zosyn for > 7 days

**Must document approved indication and order thru Meropenem order panel**.


Last updated: Jun. 17, 2025


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