System Formulary Update
First Generation Cephalosporins
Situation:
The first generation cephalosporins class review standardization was approved in the September 2024 System Pharmacy and Therapeutics Committee meeting.
Background:
The following products were reviewed: cefadroxil capsules, cefadroxil oral suspension, cefadroxil tablets, cefazolin powder for injection, cefazolin solution for injection, cephalexin capsules, cephalexin powder for oral suspension, and cephalexin tablets.
Assessment/Recommendations:
System P&T voted to include the following products on the UNC Health System Drug Formulary:
Cefazolin 1 g powder for injection
Cefazolin 1 g/50 mL intravenous solution (D5, Baxter)
Cefazolin 1 g/50 mL intravenous solution (D5, B.Braun)
Cefazolin 2 g/100 mL intravenous solution (D5, Baxter)
Cefazolin 2 g/50 mL intravenous solution (D5, B.Braun)
Cefazolin 2 g powder for injection
Cefazolin 3 g powder for injection
Cefazolin 10 g powder for injection
Cephalexin 250 mg capsule
Cephalexin 500 mg capsule
Cephalexin 50 mg/mL oral suspension
From |
To |
Cefadroxil capsule 500 mg twice daily 1 g once daily |
Cephalexin capsule 500 mg four times daily 500 mg four times daily |
Note: Stock of this formulary product may vary at individual entities
Formulary/Epic Changes will Go-Live on Tuesday, November 19, 2024