UNC Health Medication Formulary
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UNC Health Medication Formulary

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System Formulary Update
Belimumab (Benlysta) Intravenous Injection

Situation

Belimumab (Benlysta) lyophilized powder for Intravenous Injection has been approved for addition to the UNC Health Medication Formulary.

Background

Benlysta is a human monoclonal antibody indicated to treat patients 5 years and older with active, autoantibody-positive systemic lupus erythematosus who are receiving standard therapy and adults with active lupus nephritis 
who are receiving standard therapy. Benlysta is dosed at  10 mg/kg IV at 2-week intervals for the first 3 doses; followed by every 4 weeks thereafter.

It was reviewed by the System P&T Committee in July 2022 for formulary addition.

Assessment/Recommendations

The P&T Committee voted to APPROVE the addition of Benlysta to System Formulary WITH RESTRICTION to the following:

  • Inpatient use restricted to new starts for patients with active lupus nephritis
  • All other use is restricted to outpatient/clinic us only 

Formulary/Epic changes will Go-Live on Tuesday, September 13, 2022.






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