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prothrombin complex concentrate
prothrombin complex concentrate
| Drug Name |
Form |
Strength |
Notes |
| Kcentra |
POWDER FOR INJECTION, INTRAVENOUS |
vials of approximately 500 Factor IX units and 1,000 Factor IX units |
|
| Balfaxar |
|
|
|
| PCC |
|
|
|
Last updated: Jan. 29, 2025
Order via ANTITHROMBOTIC REVERSAL order set (order set 1941)
Reversal Guidelines:
Reversal in adult patients on warfarin, dabigatran, rivaroxaban, or abixaban: See Reversal Guideline 900.5010
Pediatric: Reversal of warfarin: See Reversal Guideline 900.5866
Massive Transfusion Protocol, see protocol 915.6150 and Pharmacologic Adjuncts for Massive Transfusion
5/2022: P&T Approval of fixed dosing of Kcentra for warfarin reversal for major bleeding or emergent surgery and fixed dose Kcentra for factor Xa-inhibitor reversal for major bleeding.
Other Guidelines:
Anticoagluation Management while on ECMO, see protocol 922.5063
May have limited inventory. See Antidote Policy 916.3804
Correcting coagulopathy using ROTEM: see Trauma Guideline 901.5001
For further information, see Drug Monograph.
How to Enter and Verify Blood Factor Product Orders: See Pharmacist Tip Sheet
Conversion to Balfaxar Brand Prothrombin Complex Concentrate (except LMP) Flyer