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tirofiban

tirofiban
  • Restricted Medications Cardiac Monitor (IV)
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Aggrastat Concentrate SOLUTION, INJECTABLE 3.75 mg/15 mL      
Aggrastat SOLUTION, INTRAVENOUS 5 mg / 100 ml      
Display Platelet-Aggregation Inhibitors Class : 201218
High Alert Drug : Policy
Medication comments:

tirofiban should generally not be interrupted during procedures unless there is a specific physician order.
High Alert Drug: glycoprotein IIb/IIIa inhibitors (e.g Aggrastat)
 • Electronic order sets available for ordering.
 • Bleeding Precautions sign hung in Critical Care and on Telemetry.
 • Physician/Pharmacist independently verify calculation of dose prior to administration.
 • Two RNs independently verify dosage prior to administration.
Per policy, these medications require cardiac and/or special monitoring.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes CCU, OR, PACU, CCL, ED PCU 2N (Tele) 1N (Tele), 3N (Tele) Med/Surg (1N w/o Tele, 3N w/o Tele, 4N, 5N) BirthPlace SNF ICS OPS
tirofiban (Aggrastat)
IV Infusion Key: order set		 Y Y Y N N N N N N
Anticoagulant / Antiplatelet Stoppage For Procedures
generic (Brand) Dept. Procedure Type
(hover over entry for examples)		 Stop Medication Prior To Procedure Restart after:
tirofiban
(Aggrastat)		 Anesthesia High-risk 8-24 hours Restart after 8-12 hours
Intermediate-risk 8-24 hours Restart after 8-12 hours
Low-risk 8-24 hours Restart after 8-12 hours
Patients with high risk of bleeding (eg, old age, history of bleeding tendency, concurrent uses of other anticoagulants/antiplatelets, liver cirrhosis or advanced liver disease, and advanced renal disease) undergoing low- or intermediate-risk procedures should be treated as intermediate or high risk, respectively.
Radiology
 Invasive Procedures No data
Paracentesis/Thoracentesis No data
Surgery High-risk No data Restart after No data
Low-risk No data Restart after No data
Last updated: Jan. 17, 2025
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