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sarilumab

sarilumab

Restricted Medications Non Formulary

Drug Name	Form	Strength	Non-Formulary	Restricted	TX Sub	Notes
Kevzara	INJECTION, INTRAVENOUS	200 mg

Display Interleukin-mediated Agents, Miscellaneous Class : 90242092

Medication comments:

sarilumab (Kevzara) is the alternative agent to in the setting of COVID-19.

Monoclonal Antibody agents (mAbs) not included on the NIOSH Hazardous List will not be handled as hazardous agents,
meaning the following compounding and administration processes will go into effect:
• No longer prepared with Closed System Transfer Devices (CSTD) and will be prepared in an IV bag without tubing attached
• Will be delivered with regular IV preparations
• No chemo rated PPE will be required for administration (i.e. chemo gown)
• Will not be required to be administered by a chemo certified nurse
• Will be orderable via EMR for providers

Vital signs to assess are:
• Body temperature
• Blood pressure
• Pulse rate
• Respiration rate
• Saturation of peripheral oxygen

Frequency of vital sign assessment: prior to infusion, every 15 minutes during infusion, and every 30 minutes for the hour after infusion complete.

Last updated: Sep. 5, 2025

Black Box Warnings Risk of Infections
Look-Alike/Sound-Alike sarilumab confused with adalimumab, certolizumab pegol, golimumab, siltuximab, tocilizumab

UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.