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predniSONE

predniSONE
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Deltasone SOLUTION, ORAL 5 mg/mL Conc; 5 mg/5 mL      
Deltasone TABLET, ORAL 1 mg; 5 mg; 10 mg; 20 mg      
Display Adrenals Class : 680400
Medication comments:

Per policy, these hazardous drugs have special waste requirements. 
Generic (Brand) Waste Requirements
predniSONE (Deltasone) Solutions containing alcohol ⇒  BLACK BUCKET 
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: predniSONE (Deltasone, Sterapred)
Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3)
Comments corticosteroids (oral and parenteral) Excludes inhaled and topical forms. Oral and parenteral corticosteroids may be required for conditions such as exacerbation of COPD but should be prescribed in the lowest effective dose and for the shortest possible duration.
Drug(s) ⇆ disease or syndrome corticosteroids ⇄ Delirium
Rationale Avoid in older adults with or at high risk of delirium because of the potential of inducing or worsening delirium.
If needed, use the lowest possible dose for the shortest duration and monitor for delirium.
Recommendation Avoid, except in situations listed under the rationale statement.
 Quality of evidence: Moderate, Strength of Recommendation: Strong
Last updated: Sep. 24, 2025
  • Hazardous Waste BLACK BUCKET
  • Look-Alike/Sound-Alike predniSONE confused with prednisoLONE
UpToDate Lexidrug

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