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phenylephrine

phenylephrine
  • Restricted Medications Cardiac Monitor (IV)
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Neo-Synephrine SOLUTION, INJECTABLE 1 mg/10 mg/mL; 10 mg/1 mL; 50 mg/5 mL      
Neo-Synephrine SOLUTION, INTRAVENOUS 50 mg/250 mL drip      
Display alpha-Adrenergic Agonists Class : 121204
Medication comments:
Warning: Pump Care Area Special Med!
phenylephrine should generally not be interrupted during procedures unless there is a specific physician order.
Per policy, these medications require cardiac and/or special monitoring.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes CCU, OR, PACU, CCL, ED PCU 2N (Tele) 1N (Tele), 3N (Tele) Med/Surg (1N w/o Tele, 3N w/o Tele, 4N, 5N) BirthPlace SNF ICS OPS
phenylephrine (Neo-Synephrine)
IV Infusion vasopressor		 Y N N N N Y
(IV Push by ANES)		 N N N
Iredell Memorial Hospital ICU Adult Infusion Guidelines  
The following orders are intended to provide a specific, safe, and effective means of initiating and titrating medications for critically ill patients. Physicians may modify doses and/or parameters as necessary pending patients' status.For all medications listed below, the responsible LIP is to be notified if unable to titrate or the maximum dose is reached andgoals of therapy are not met.
Drug Name Onset Preparation Compatible fluids
phenylephrine (Neo-Synephrine) seconds 10 mg/100 ml NS or D5W
Starting Dose for ICU Sedation Titration Guidelines (for increasing and decreasing doses) with Maximum dose
Begin infusion at 50 mcg/min. titrate by 5 mcg/min every 5 min to keep MAP ≥ 65. Max = 450 mcg/min.
Adult Extravasation Management
phenylephrine (Neo-Synephrine)
Agent type: Non-Chemotherapeutic
Vesicant/Irritant: Vesicant
Local Care: Warm compress
Antidote: Phentolamine injection, nitroglycerin topical 2% ointment, or terbutaline
Antidote link(s):
Comments: • Phentolamine preferred 1st line
Last updated: Aug. 27, 2025
UpToDate Lexidrug

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