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meropenem

meropenem

Drug Name	Form	Strength	Non-Formulary	Restricted	TX Sub	Notes
Merrem	POWDER FOR INJECTION, INTRAVENOUS	500 mg; 1 g; 2g

Display Carbapenems Class : 08120708

Medication comments:

Per policy, these drugs are subject to renal dosing adjustments by pharmacy.
Generic + Route (Brand) • Indications	Usual Adult Dose Comments	Renal Dosage Adjustments
meropenem IV (Merrem^©) • CNS infections • Necrotizing fasciitis • Bone/Joint Infection	2 gm q8h (3 hr infusion) Refer to	CrCl > 50 mL/min: No adjustment necessary CrCl 25-49 mL/min: 2 gm q12h CrCl 10-24 mL/min: 1 gm q12h CrCl < 10 mL/min, HD: 1 gm q24h (give dose after HD) Continuous renal replacement therapy (CRRT): 2 gm q12h
meropenem IV (Merrem^©) • Pseudomonas infection (susceptible to meropenem) • Acinetobacter infection (susceptible to meropenem)	1 gm q8h (3 hr infusion) Refer to	CrCl > 50 mL/min: No adjustment necessary CrCl 25-49 mL/min: 1 gm q12h CrCl 10-24 mL/min: 500 mg q12h CrCl < 10 mL/min, HD: 500 mg q24h (give dose after HD) Continuous renal replacement therapy (CRRT): 1 gm q12h
meropenem IV (Merrem^©) • Pneumonia • Intra-abdominal infection • Neutropenic fever • Infections caused by ESBLs or cefTRIAXone-resistant organisms	500 mg q6h (30 min infusion) Refer to	CrCl > 50 mL/min: No adjustment necessary CrCl 25-49 mL/min: 500 mg q8h CrCl 10-24 mL/min: 500 mg q12h CrCl < 10 mL/min, HD: 500 mg q24h (give dose after HD) Continuous renal replacement therapy (CRRT): 500 mg q6h

Per policy, these antibiotic medications may be given IV push. Adult Patients Only!
generic (Brand) Strength	Copy/Paste comments for PharmNet
meropenem (Merrem) 500 mg vial	Dilute with 10 ml Sterile Water for Injection and give over 3-5 mins.

Last updated: Mar. 17, 2025

Renal Adjustment Policy meropenem subject to adjustments by pharmacy.

UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.