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imipenem-cilastatin-relebactam

imipenem-cilastatin-relebactam
  • Restricted Medications Infectious Disease Services use only
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Recarbrio POWDER FOR INJECTION, INTRAVENOUS 500 mg-500 mg-250 mg      
Display Carbapenems Class : 08120708
Medication comments:

Per policy, use of these medications is restricted as noted below:  
generic (Brand) Restrictions
imipenem/cilastatin/relebactam (Recarbrio) ID use only
Per policy, these drugs are subject to renal dosing adjustments by pharmacy. 
Generic + Route
(Brand)
• Indications		 Usual Adult Dose
Comments		 Renal Dosage Adjustments
imipenem-cilastatin-relebactam IV
(Recarbrio©)		 1.25 gm q6h
(30 min infusion)
Restricted to ID only!		 CrCl ≥ 90: No adjustment necessary
CrCl 60 - 89: 1 g q6h
CrCl 30 - 59: 750 mg q6h
CrCl 15 - 29: 500 mg q6h
CrCl <15: In the absence of data, 500 mg q12h may be considered.
HD/PD: 500 mg q6 - 8h
Last updated: Dec. 8, 2025
  • Renal Adjustment Policy
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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