Search results for:

famotidine

famotidine
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Pepcid LIQUID, ORAL 40 mg/5 mL      
Pepcid SOLUTION, INTRAVENOUS 20 mg/2mL      
Pepcid TABLET, ORAL 10 mg; 20 mg      
Display Histamine H2-Antagonists Class : 562812
Medication comments:

Refrigerator item (injection) 

Per policy, these drugs are subject to renal dosing adjustments by pharmacy. 
Generic + Route
(Brand)
• Indications		 Usual Adult Dose
Comments		 Renal Dosage Adjustments
famotidine IV/PO
(Pepcid©)		 40 mg q24h
or
20 mg q12h		 IV Adjustments:
CrCl > 50: 20 mg BID
CrCl < 50: 20 mg daily
PO Adjustments:
CrCl > 60: 20 mg daily or BID
CrCl 30-60: 10-20 mg daily
CrCl < 30: 10 mg daily or 20 mg QOD
Per policy, these drugs may be converted from IV to PO in patients who meet criteria.  
famotidine (Pepcid) may convert from IV to PO on a mg-to-mg basis.
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: famotidine (Pepcid)
Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3)
Drug(s) ⇆ disease or syndrome H2-receptor antagonists ⇄ Delirium
Rationale Avoid in older adults with or at high risk of delirium because of the potential of inducing or worsening delirium.
Recommendation Avoid
 Quality of evidence: Low, Strength of Recommendation: Strong
 
Criteria 5: medications that should be avoided or have their dosage reduced with varying levels of kidney function in older adults. (Table 6)
CrCl (mL/min) at which action is required <50
Rationale Mental status changes
Recommendation Reduce dose
 Quality of evidence: Moderate, Strength of Recommendation: Strong
Last updated: Sep. 19, 2025
  • Renal Adjustment Policy famotidine subject to adjustments by pharmacy.
  • IV to PO Conversion Policy Policy
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.
Copyright © 2026 Rpharmy, LLC ­ All Rights Reserved