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dexAMETHasone

dexAMETHasone
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Decadron LIQUID, ORAL 0.5 mg/5 mL      
Decadron SOLUTION, INJECTABLE 4 mg/mL; 10 mg/mL      
Decadron SOLUTION, OPHTHALMIC 0.1%      
Decadron TABLET, ORAL 4 mg; 6 mg      
Display Adrenals Class : 680400
Medication comments:

Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent Formulary Equivalent
dexamethasone (Decadron) 0.1% cream triamcinolone (Kenalog) 0.1% cream
Per policy, these hazardous drugs have special waste requirements. 
Generic (Brand) Waste Requirements
dexAMETHasone (Decadron) Solution, injection contain alcohol ⇒  BLACK BUCKET 
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: dexamethasone (Decadron)
Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3)
Comments corticosteroids (oral and parenteral) Excludes inhaled and topical forms. Oral and parenteral corticosteroids may be required for conditions such as exacerbation of COPD but should be prescribed in the lowest effective dose and for the shortest possible duration.
Drug(s) ⇆ disease or syndrome corticosteroids ⇄ Delirium
Rationale Avoid in older adults with or at high risk of delirium because of the potential of inducing or worsening delirium.
If needed, use the lowest possible dose for the shortest duration and monitor for delirium.
Recommendation Avoid, except in situations listed under the rationale statement.
 Quality of evidence: Moderate, Strength of Recommendation: Strong
Last updated: Sep. 18, 2025
  • Hazardous Waste BLACK BUCKET
  • Look-Alike/Sound-Alike dexAMETHasone confused with dexmedeTOMIDine
UpToDate Lexidrug

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Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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