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cycloSPORINE IV

cycloSPORINE IV
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
SandIMMUNE SOLUTION, INJECTABLE 50 mg/mL      
Display Immunomodulatory Agents, Immunosuppressive Agents Class : 922000, 924400
Medication comments:
USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances.
The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense] NIOSH Group
cycloSPORINE (Gengraf, Neoral, SandIMMUNE) PO [UD ⇒ UD] Non - Antineoplastic
Pharmacy:
Receiving /
Storage /
Preparation

Exposure Risk:
minimal
 • Handling/preparation PPE Requirements: n/a
• Receiving from Distributor: Standard
• Pharmacy Storage Area: Carousel
• Packaging/Reconstitution Location: n/a
• Compounding (Non-Sterile/Sterile) Location: n/a
• Omnicell Load: No
Transport • Transport (dose is placed inside a plastic sealable bag): Standard
Nursing:
Storage /
Admin.

Exposure Risk:
low
 • Handling/administration PPE Requirements: Single pair of CX approved gloves; Wash hands after handling
• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
• Signage on Patient Door Required: No
• Manipulation of Dosage Form: Standard
• Special Manipulation for Administration: do not open capsule
Disposal /
Spills		 • Disposal of Drug Waste: Full-  blue bin , trace/packaging- trash
• Disposol of Used PPE: trash bin (inside plastic bag)
• Spill management: n/a
NIOSH Supplemental Information: IARC Group 1 carcinogen; NTP
Reason for exemption of USP<800> Containment Requirements: Purchased in final dosage form; packaged as unit dose. Does not require additional manipulation for dispensing.
Last updated: Jun. 18, 2025
  • Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug
  • Hazardous Waste BLACK BUCKET
  • Black Box Warnings Infection, neoplasm, nephrotoxicity risk
  • Look-Alike/Sound-Alike cycloSPORINE confused with cycloSERINE, cycloSPORINE modified
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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