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aztreonam-avibactam

aztreonam-avibactam
  • Restricted Medications Infectious Disease Services use only
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Emblaveo POWDER FOR INJECTION, INTRAVENOUS 1.5 gm-0.5 gm      
Display Monobactams Class : 08120716
Medication comments:

Per policy, use of these medications is restricted as noted below:  
generic (Brand) Restrictions
aztreonam/avibactam (Emblaveo) ID use only
Per policy, these drugs are subject to renal dosing adjustments by pharmacy. 
Generic + Route
(Brand)
• Indications		 Usual Adult Dose
Comments		 Renal Dosage Adjustments
aztreonam-avibactam IV
(Emblaveo©)		 2.67 gm x1, then 2 gm q6h
(3 hr infusion)
Restricted to ID only!		 CrCl > 50: No adjustment necessary
CrCl 30 - 50: Loading dose: 2.67 gm once, then 1 gm q6h
CrCl 15-30: Loading dose: 1.8 gm once, then 900 mg q8h
CrCl ≤ 15: Loading dose: 1.33 gm once, then 900 mg q12h
HD: 1.33 gm once then 900 mg q12h; Administer dose after HD on dialysis day
Last updated: Dec. 8, 2025
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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