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azithromycin

azithromycin
  • Restricted Medications Oral suspensions restricted to patients being admitted or already admitted.
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Zithromax POWDER FOR INJECTION, INTRAVENOUS 500 mg      
Zithromax SUSPENSION, ORAL 250 mg / 5 ml; 500 mg / 5 ml      
Zithromax TABLET, ORAL 250 mg; 500 mg      
Display Other Macrolides Class : 08121208
Medication comments:
Per policy, use of these medications is restricted as noted below:  
generic (Brand) Restrictions
azithromycin (Zithromax) Oral suspensions restricted to patients being admitted or already admitted.
Per policy, these drugs are subject to renal dosing adjustments by pharmacy. 
Generic + Route
(Brand)
• Indications		 Usual Adult Dose
Comments		 Renal Dosage Adjustments
azithromycin IV
(Zithromax©)		 500 mg daily No adjustment necessary
azithromycin PO
(Zithromax©)		 250-500 mg daily
(500-1,000 mg
single dose for
specific indications)		 No adjustment necessary
Per policy, these drugs may be converted from IV to PO in patients who meet criteria.  
Generic
(Brand)		 Population IV Dose PO Dose Notes
azithromycin
(Zithromax)		 adult 250 mg IV q24h 250 mg PO q24h Although azithromycin has low bioavailability, it is well-distributed to tissues.
500 mg IV q24h 500 mg PO q24h
pediatric 5-10 mg/kg q24h 5-10 mg/kg q24h
(max: 500 mg/day)
Pediatric Pharmacy Association 2025 KIDs List of Key Potentially Inappropriate Drugs in Pediatrics 
Medication: azithromycin (Zithromax)
Key Potentially Inappropriate Drugs in Pediatrics (KIDs) List: Second Edition (Table 1)
Drug macrolides
Risk/Rationale Hypertrophic pyloric stenosis (risk greater for erythromycin > azithromycin)
Recommendation Avoid in younger than 1 mo except for Bordetella pertussis (azithromycin) or Chlamydia trachomatis pneumonia (azithromycin and erythromycin).
Caution in younger than 1 mo for Ureaplasma (azithromycin)
 Quality of evidence: High, Strength of Recommendation: Strong
Last updated: Dec. 29, 2025
  • Renal Adjustment Policy azithromycin subject to adjustments by pharmacy.
  • IV to PO Conversion Policy Policy
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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