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EPINEPHrine

EPINEPHrine
  • Restricted Medications Cardiac Monitor (IV infusion)
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Primatene Mist Inhaler AEROSOL, INHALATION (Non-formulary)      
EpiPen Auto-Injector KIT, INJECTABLE 0.15 mg, 0.3 mg syringe      
Adrenalin SOLUTION, INJECTABLE 1 mg/10 mL (syringe);1 mg/mL (amp)      
EPINEPHrine SOLUTION, INTRAVENOUS 4 mg/250 mL drip      
Display alpha and beta-Adrenergic Agonists, Expectorants Class : 121212, 481600
Medication comments:
Warning: Pump Care Area Special Med!
EPINEPHrine should generally not be interrupted during procedures unless there is a specific physician order.
Per policy, these medications require cardiac and/or special monitoring.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes CCU, OR, PACU, CCL, ED PCU 2N (Tele) 1N (Tele), 3N (Tele) Med/Surg (1N w/o Tele, 3N w/o Tele, 4N, 5N) BirthPlace SNF ICS OPS
EPINEPHrine (Adrenalin)
IV Infusion vasopressor		 Y N N N N N N N N
Iredell Memorial Hospital ICU Adult Infusion Guidelines  
The following orders are intended to provide a specific, safe, and effective means of initiating and titrating medications for critically ill patients. Physicians may modify doses and/or parameters as necessary pending patients' status.For all medications listed below, the responsible LIP is to be notified if unable to titrate or the maximum dose is reached andgoals of therapy are not met.
Drug Name Onset Preparation Compatible fluids
EPINEPHrine (Adrenalin) minutes 4 mg/250 ml NS or D5W
Starting Dose for ICU Sedation Titration Guidelines (for increasing and decreasing doses) with Maximum dose
For symptomatic bradycardia: Begin infusion at 2 mcg/min. titrate by 1 mcg/min every 5 min to keep MAP ≥ 65. Max = 10 mcg/min.
Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent Formulary Equivalent
EPINEPHrine inhaler (Primatene Mist) albuterol inhaler
Adult Extravasation Management
EPINEPHrine (Adrenalin)
Agent type: Non-Chemotherapeutic
Vesicant/Irritant: Vesicant
Local Care: Warm compress
Antidote: Phentolamine injection, nitroglycerin topical 2% ointment, or terbutaline
Antidote link(s):
Comments: • Phentolamine preferred 1st line
Last updated: Aug. 27, 2025
  • Therapeutic Interchange Policy albuterol (Ventolin)
  • Look-Alike/Sound-Alike EPINEPHrine confused with ePHEDrine
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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