Search results for:

DAPTOmycin

DAPTOmycin
  • Restricted Medications Infectious Disease Services use only
Drug Name Form Strength Non-Formulary Restricted TX Sub Notes
Cubicin POWDER FOR INJECTION, INTRAVENOUS 500 mg      
Display Cyclic Lipopeptides Class : 08122812
Medication comments:

DAPTOmycin Rounded Dosing Using Pre-mix Bags
DAPTOmycin Dosing Weight * Total
Daily Dose		 Dose Range
6 mg/kg 40-60 kg 350 mg 7.5-5 mg/kg
61-100 kg 500 mg 8.1-5 mg/kg
101-145 kg 700 mg 6.9-4.8 mg/kg
>145 kg 1,000 mg Maximum 6.9 mg/kg
8 mg/kg 40-45 kg 350 mg 7.5-6.7 mg/kg
46-75 kg 500 mg 10.9-6.7 mg/kg
76-105 kg 700 mg 9.2-6.7 mg/kg
>105 kg 1,000 mg Maximum 9.4 mg/kg
10 mg/kg 40-65 kg 500 mg 12.5-7.7 mg/kg
66-85 kg 700 mg 10.6-8.2 mg/kg
>85 kg 1,000 mg Maximum 11.8 mg/kg
 * Use total body weight (TBW) for non-obese (BMI <30).
  In obese patients (BMI ≥30), use Adjusted Body Weight (ABW).
Per policy, use of these medications is restricted as noted below:
generic (Brand) Restrictions
DAPTOmycin (Cubicin) ID use only
Per policy, these drugs are subject to renal dosing adjustments by pharmacy. 
Generic + Route
(Brand)
• Indications		 Usual Adult Dose
Comments		 Renal Dosage Adjustments
DAPTOmycin IV
(Cubicin©)
• Not for pneumonia		 4-6 mg/kg q24h
Actual body weight
Restricted to ID only!		 CrCl ≥ 30: No adjustment necessary
CrCl < 30: 4-6 mg/kg q48h
HD: 6 mg/kg, 6 mg/kg, 8 mg/kg (72 hour period) 3x/week w/ dialysis
Last updated: Jun. 1, 2026
  • Renal Adjustment Policy DAPTOmycin subject to adjustments by pharmacy.
  • Look-Alike/Sound-Alike DAPTOmycin confused with DACTINomycin
UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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