Approved Hospital Formulary
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Medications not yet evaluated by P&T are considered NON-FORMULARY. Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step!
Please be sure to document all clinical activities daily.
Please be sure to document all clinical activities daily.
Approved Hospital Formulary
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DAPtomycin
DAPtomycin
- Restricted Miscellaneous Program Formulary
- Restricted Cubicin --> Restricted to Infectious Diseases providers ~OR~ any prescriber for acute skin and skin structure infections.
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Last updated: Jun. 12, 2025
DAPtomycin is classified as formulary, restricted; use for skin and skin structure infections is approved for all prescribers (6 mg/kg once daily dose recommended). Treatment of all other infectious diseases is restricted to ID.
Dose Rounding: Nearest 50 mg increment for patients 18 years and over. Use total body weight in non-obese patients and adjusted body weight in obese patients (obese if TBW/IBW is ≥130% or BMI ≥30).
Recommended AdjBW equation for daptomycin: AdjBW = IBW + 0.4(TBW-IBW)
Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information. CrCl calculation policy available here.
Weekly CPK monitoring.
Reviewed: 26 May 2015 (Cubicin), June 2020 (Administration Time), May 2025
Daptomycin SBAR Update May 2025.pdf